Joan Montero, Ph.D.
Instructor in Medicine
Hello dear reader! My name is Joan Montero, I am originally from a wonderful Mediterranean city, Barcelona, and came to the Letai lab some time ago pursuing a very simple idea: to give cancer patients a better chance to fight this terrible disease. I know that it may sound naive and utopic, but honestly that was my main reason to join the lab, and I have to say that I am very satisfied with all the progress we have made in the field and. I can only describe my experience in Boston so far as fantastic, both personally and professionally.
I completed my PhD training working on cell death and liver cancer at Universitat de Barcelona / Consejo Superior de Investigaciones Científicas in Barcelona (Catalonia, Spain). As a scientist, I have been always interested in programmed cell death because it can explain why some therapies are not effective to treat cancer patients, and this knowledge can be used to find more effective treatments against this disease. My work at the Letai lab consisted in designing diagnostic tests for precision medicine, resulting in a novel technique called Dynamic BH3 Profiling (DBP) that predicts response to anticancer therapy in vitro, in vivo and in patient samples, by measuring changes in the mitochondrial apoptotic competency, and can be used as a predictive biomarker for personalized cancer therapy. I am currently involved in several studies to find rational combinations of therapies, emphasizing the use of targeted therapies and BH3 mimetics, to treat different types of cancer.
Click HERE for my Pubmed.